Danazol in non-splenectomized patients with refractory idiopathic thrombocytopenic purpura.
نویسندگان
چکیده
منابع مشابه
Danazol in non-splenectomized patients with refractory idiopathic thrombocytopenic purpura.
Seven non-splenectomized patients with chronic refractory idiopathic thrombocytopenic purpura were treated with danazol 800 mg daily. All were glucocorticoid failures and four were refractory to all additional previous therapy. Five patients benefited from danazol and in two sustained normal platelet counts, for over 44 and 51 months, were observed. We conclude that danazol is useful for long t...
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Eight non-splenectomized patients with corticosteroid-refractory idiopathic thrombocytopenic purpura (ITP) were treated with low-dose vincristine (1 mg/week up to a total dose of 4 mg). Complete remission was achieved in 2 cases and partial remission in 3. Bleeding stopped in one patient who failed to remit. No statistical relationship was found between the response to vincristine and the durat...
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Abstract Background Immune thrombocytopenic purpura (ITP) is a common autoimmune bleeding condition in children that is characterized by a decrease in the platelet count. The aims of this study were to define epidemiologic features of patients with primary ITP who were admitted to Mofid Children's Hospital, Tehran, Iran, in a 5-year period. Methods We retrospectively studied the records of ...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1990
ISSN: 0032-5473
DOI: 10.1136/pgmj.66.780.827